Anti-donor specific immunosuppression without global suppression

Dendritic Cell Engulfs LactobacilliThe Kang Lab is developing novel strategies for the induction of transplant-specific tolerance.  This work is a critically important step toward the establishment of immunotherapy in human transplant recipients to prevent organ rejection without relying on immunosuppressive drugs that inhibit the entire immune system.

Recent Publications

Brennan TV, Jaigirdar A, Hoang V, Hayden T, Liu FC, Zaid H, Chang CK, Bucy RP, Tang Q, Kang SM
Preferential priming of alloreactive T cells with indirect reactivity.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, Apr-01-2009; 94: 709-18
Brennan TV, Hoang V, Garrod KR, Liu FC, Hayden T, Kim J, Kang SM
A new T-cell receptor transgenic model of the CD4+ direct pathway: level of priming determines acute versus chronic rejection.
Transplantation, Jan-27-2008; 852: 247-55
View all Publications »